Dutasteride, however, is a so-called dual inhibitor with both 5α-R1 and 5α-R2 inhibition. IC50 for 5α-R1 is 7 nM but 6 nM for 5α-R2. As mentioned above, it reduces DHT > 90% overall, or precisely % and for intraprostatic DHT the reduction is 97-99%. Dutasteride has also been found to inhibit 5α-R3, in vitro, with IC50= nM.  The 2,5-difluorophenyl side chain on the D-ring of the compound shows significant lipophilic features and as increased lipophilicity enhances the potency of the compounds binding at pocket site, its potency is much greater than of finasteride. 
In February 2017, American triathlete Beth Gerdes was given a 2-year suspension for presence of ostarine, and American triathlete Lauren Barnett was given a 6-month suspension for the presence of Ostarine. Both triathletes claimed contamination from salt tablet supplements. Lauren Barnett was able to provide tablets and sealed bottle tablets which both tested positive for contamination, thus only the 6-month suspension. The 2-year suspension still stands for Beth Gerdes who provided tablets for testing, but tests showed only low levels of ostarine not high enough to confirm the finding. 
Why a report on castor oil? Castor oil is one of the most versatile plant oils. Its unique chemical structure makes it useful in a wide number of industries and applications. Castor oil is fast becoming one of the most sought after plant oils, owing to its rich properties and variety of end-uses. Currently, it is being used by industries from pharmaceuticals to lubricants. With biopolymer and bio-fuels industries picking up a lot of steam in the last couple of years, the potential for castor oil to play a much larger role in the world economy had increased dramatically. While the castor oil industry is over five decades old, there has been considerable interest shown in this industry in the last few years. Leading countries from practically every continent (North & South America, Europe, Asia, Africa and Oceania) are showing renewed interest in the castor crop.