Male sex hormones are

Are your hormones in tune? Mounting evidence suggests that exposure to light at night -- whether you're asleep or awake --  might play a crucial role in cancer, diabetes, and obesity. The World Health Organization classified "circadian disruption" as probably carcinogenic, and light at night is considered by some to be an endocrine disruptor that may affect melatonin, cortisol, ghrelin, leptin, and testosterone. "Most people think, and the drug companies want you to think, that waking up at night is bad for you," says Richard Stevens, ., a cancer epidemiologist at the University of Connecticut health center. But that's not the case, he says -- it's exposure to light at night that's the problem. "If you wake up at night, as most of us do, that is a period of quiet wakefulness -- stay in bed, in the dark, and enjoy it," Stevens suggests.

When measuring testosterone levels, it is critical to determine the levels of both free and total testosterone to understand the cause of any observed symptoms of deficiency (Khosla et al 2008).

Because of difficulties with equipment standardization and inter-laboratory variability, it is recommended that physicians consistently use the same local laboratories and gain familiarity with the accuracy, precision and definition of normal values for the assays offered in their communities (Morales et al 2010).

The SHBG-bound fraction is not biologically active, but the albumin-bound and free fractions are. Reduction in free but not total testosterone is associated with diminished libido 107,108 and potency. Testosterone increases potency and libido, whereas estradiol lowers it. Although estradiol constitutes only 1% of male gonadal steroids, it exerts almost 50% of the negative feedback on male LH secretion. 110 Hepatic enzyme-inducing AEDs lower the amount of free or biologically active testosterone available to stimulate sexual function; at the same time they increase the serum level of estradiol, which actively inhibits it.

Genitals  – Testes will lessen quite significantly in size.  The production of testosterone and sperm is also greatly reduced.  Penile size will also likely diminish.  Sexual function will decrease, but the extent to which performance is affected is unpredictable. Erections may still continue, but will probably be less frequent, and not last as long, and in some cases may not be possible. Ejaculate will lessen, probably to the point of only producing a very small, clear discharge as a result of the prostate and the associated structures responsible for semen production being impeded.  It is important to note, however, that the ability to orgasm is not dependent on either an erection, nor ejaculate.  Anecdotally speaking, many transgender females report greater satisfaction with their orgasms after these changes occur in their genitals.

Male sex hormones are

male sex hormones are

Genitals  – Testes will lessen quite significantly in size.  The production of testosterone and sperm is also greatly reduced.  Penile size will also likely diminish.  Sexual function will decrease, but the extent to which performance is affected is unpredictable. Erections may still continue, but will probably be less frequent, and not last as long, and in some cases may not be possible. Ejaculate will lessen, probably to the point of only producing a very small, clear discharge as a result of the prostate and the associated structures responsible for semen production being impeded.  It is important to note, however, that the ability to orgasm is not dependent on either an erection, nor ejaculate.  Anecdotally speaking, many transgender females report greater satisfaction with their orgasms after these changes occur in their genitals.

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